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Changing the way the world treats chronic diseases— with exercise!

Welcome to StarkTx

​​Current Stark Therapeutics updates & contact —all in one place

Our Science

Durable Gene Silencing to Mimic Exercise 

Exercise takes shape in many forms 

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and helps fight the drivers of 

chronic metabolic disorders

We look at exercise from the genetic level

Introducing STK-AVi

An engineered viral vector targeting  skeletal muscle to mimic exercise

RNAi

AAV

interference RNA silences

STK-AVi uses RNAi to suppress genes related to exercise
Exercise
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Target Gene
microRNA is naturally produced by cells to suppress genes in response to cellular states
STK-AVi
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1X
Target Gene
RNAi is engineered to suppress specific genes to mimic cellular states 

durability comes from

delivery

We target skeletal muscle using an engineered viral vector for durable suppression

because exercise is valuable everyday

Pipeline

Applying Exercise to Therapeutics
Program
Indication
Status
STK-AVi

AAV & RNAi 

​

T2DM
Discovery
Lead Op
Preclinical
IND
Ph1
STK-AVi
MASH

AAV & RNAi 

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Discovery
Lead Op
Preclinical
IND
Ph1
STK-AVi

AAV & RNAi 

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Rare 
Undisclosed
Discovery
Lead Op
Preclinical
IND
Ph1

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